Disentangling Short-Run COVID-19 Price Impact Pathways in the US Corn Market

Despite this focus on pandemic-related supply chain disruptions, fewer empirical studies have sought to isolate short-term price impacts in food and nonfood agricultural commodity markets.1 Understanding the drivers of short-term commodity price impacts is critical to understanding future susceptibility to major market shocks and to informing policies related to shock mitigation. Declines in ethanol production reached an estimated 2 billion gallons lost from March to November 2020, leading to a corresponding decline of 700 million bushels of corn usage and a loss of billions of dollars of ethanol producer surplus (Renewable Fuels Association, 2020b;Schmitz, Moss, and Schmitz, 2020). Increases in corn-based ethanol production that started in 2005 have linked agricultural commodity prices and energy markets as US ethanol production increased rapidly from 3.9 billion gallons in 2005 to 13.3 billion by 2010 and 15.8 billion by 2019 (Chakravorty, Hubert, and Nøstbakken, 2009;Wright, 2011;Roberts and Schlenker, 2013;Asgari, Saghaian, and Reed, 2020;US Department of Agriculture, 2021). Given that over 90% of US ethanol is used in mixtures of E10 gasoline and the US market reached a 10% "blend wall" in 2016, any reduction in gasoline use will cause proportional decreases in ethanol use (US Energy Information Administrationa, 2020;US Department of Agriculture, 2021).

Pharmacologic therapies of ARDS: From natural herb to nanomedicine.

Acute respiratory distress syndrome (ARDS) is a common critical illness in respiratory care units with a huge public health burden. Despite tremendous advances in the prevention and treatment of ARDS, it remains the main cause of intensive care unit (ICU) management, and the mortality rate of ARDS remains unacceptably high. The poor performance of ARDS is closely related to its heterogeneous clinical syndrome caused by complicated pathophysiology. Based on the different pathophysiology phases, drugs, protective mechanical ventilation, conservative fluid therapy, and other treatment have been developed to serve as the ARDS therapeutic methods. In recent years, there has been a rapid development in nanomedicine, in which nanoparticles as drug delivery vehicles have been extensively studied in the treatment of ARDS. This study provides an overview of pharmacologic therapies for ARDS, including conventional drugs, natural medicine therapy, and nanomedicine. Particularly, we discuss the unique mechanism and strength of nanomedicine which may provide great promises in treating ARDS in the future.

The Effect of Collectivism on Mental Health during COVID-19: A Moderated Mediation Model.

BACKGROUND: COVID-19 is an unprecedented public health emergency of international concern and has caused people to live in constant fear and posed a significant threat to their physical and mental health. METHOD: The study constructed a moderated mediation model to examine the mediating role of emotion regulation between collectivism and mental health and the moderating role of ego identity in the context of COVID-19. A total of 459 participants were recruited to complete the survey from 30 January to 8 May 2021.The Mental Health in COVID-19 Period Scale, Collectivism Tendency Scale, ERQ, and Identity Status Scale were used for the study. RESULTS: (1) Expressive suppression played a mediating role in the relationship between collectivism and mental health; (2) The direct effect of collectivism on mental health and the path from expressive suppression to mental health were moderated by ego identity. CONCLUSION: The effect of collectivism on mental health is indirectly generated through expressive suppression and ego identity showing different patterns of regulation of mental health in different pathways, and its mechanisms and other important influences could be further explored in the future.

Equity-Driven Sensing System for Measuring Skin Tone–Calibrated Peripheral Blood Oxygen Saturation (OptoBeat): Development, Design, and Evaluation Study

Background: Many commodity pulse oximeters are insufficiently calibrated for patients with darker skin. We demonstrate a quantitative measurement of this disparity in peripheral blood oxygen saturation (SpO2) with a controlled experiment. To mitigate this, we present OptoBeat, an ultra–low-cost smartphone-based optical sensing system that captures SpO2 and heart rate while calibrating for differences in skin tone. Our sensing system can be constructed from commodity components and 3D-printed clips for approximately US $1. In our experiments, we demonstrate the efficacy of the OptoBeat system, which can measure SpO2 within 1% of the ground truth in levels as low as 75%. Objective: The objective of this work is to test the following hypotheses and implement an ultra–low-cost smartphone adapter to measure SpO2: skin tone has a significant effect on pulse oximeter measurements (hypothesis 1), images of skin tone can be used to calibrate pulse oximeter error (hypothesis 2), and SpO2 can be measured with a smartphone camera using the screen as a light source (hypothesis 3). Methods: Synthetic skin with the same optical properties as human skin was used in ex vivo experiments. A skin tone scale was placed in images for calibration and ground truth. To achieve a wide range of SpO2 for measurement, we reoxygenated sheep blood and pumped it through synthetic arteries. A custom optical system was connected from the smartphone screen (flashing red and blue) to the analyte and into the phone’s camera for measurement. Results: The 3 skin tones were accurately classified according to the Fitzpatrick scale as types 2, 3, and 5. Classification was performed using the Euclidean distance between the measured red, green, and blue values. Traditional pulse oximeter measurements (n=2000) showed significant differences between skin tones in both alternating current and direct current measurements using ANOVA (direct current: F2,5997=3.1170 × 105, P<.01;alternating current: F2,5997=8.07 × 106, P<.01). Continuous SpO2 measurements (n=400;10-second samples, 67 minutes total) from 95% to 75% were captured using OptoBeat in an ex vivo experiment. The accuracy was measured to be within 1% of the ground truth via quadratic support vector machine regression and 10-fold cross-validation (R2=0.97, root mean square error=0.7, mean square error=0.49, and mean absolute error=0.5). In the human-participant proof-of-concept experiment (N=3;samples=3 × N, duration=20-30 seconds per sample), SpO2 measurements were accurate to within 0.5% of the ground truth, and pulse rate measurements were accurate to within 1.7% of the ground truth. Conclusions: In this work, we demonstrate that skin tone has a significant effect on SpO2 measurements and the design and evaluation of OptoBeat. The ultra-low-cost OptoBeat system enables smartphones to classify skin tone for calibration, reliably measure SpO2 as low as 75%, and normalize to avoid skin tone–based bias.